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Dupuytren's contracture

From Surgopaedia

Also called palmar fibromatosis and Dupuytren disease

Risk factors

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  • Genetics
  • Ethnicity
  • Workers exposed to repetitive handling or vibration
  • Diabetes
  • Smoking and alcohol

Aetiology

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  • Unknown

Pathophysiology

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  • Progressive fibrosis of the palmar fascia - fibroblastic proliferation and disorderly collagen deposition
  • Benign, slowly progressive fibroproliferative disease
  • Starts as a nodule, progresses to cords and joint stiffness and loss of full extension over decades

Presentation

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  • Usually painless
  • Often rubs the palms and fingers in an attempt to straighten them out
  • Most commonly fourth, then fifth fingers


Diagnosis

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  • Clinical - history of painless loss of finger extension
  • Palpable clinical findings

Treatment

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  • Mild: protect fingers/hand while working (gloves); no evidence for massage or stretching
  • Persistent/progressive symptoms: intralesional glucocorticoid injection if local tenderness is bothersome
  • Contractures or functional impairment: surgery
    • Better long-term outcomes than percutaneous approaches
    • Some say need an angle >30-40 degrees at MCPJ to benefit
    • Either transect cords (fasciotomy) or excise diseased cords (fasciectomy), with or without excision of the overlying skin