Editing Platelet transfusion


== Indications ==

* Platelet cut-off of 50 is reasonable for invasive procedures - give 1 unit and assess response

== Components available ==

* '''Apheresis:''' 280 x10^9 in 210mL
** Collected from a single donor by using an apheresis machine with an integrated leucoreduction system, then returns the remaining blood back to the donor
** Have higher residual plasma content
** Much more costly
** Indications:
*** Requirement for HLA compatible and/or HPA matched platelets 
*** Patients who require IgA deficient platelets
*** Neonates/small children whose platelet dose requirement can be met by a split apheresis component, to avoid wastage of part of a pooled bag
* '''Pooled:''' 290 x 10^9 in 370mL
** Produced via the Buffy Coat method - pooled from separate ABO-identical whole blood donations using a platelet additive solution, then centrifuged, filtered and rested to produce a leucodepleted pooled platelet unit
* '''Paed:''' 75 x 10^9 in 55mL

== Administration ==

* Expected rise in a 70kg stable adult is 20-40 x 10^9/L
* Give over 30 mins
* '''In an adult, generally give 1 unit pooled''' (or apheresis if they have a specific indication)

[[Category:Haematology]]