Editing Acute pancreatitis (section)

== '''Autoimmune pancreatitis''' ==

* Uncommon overall
* Not commonly a cause of ACUTE pancreatitis
* Suspect in those with painless obstructive jaundice (most common) or diffusely enlarged pancreas on imaging, who have other autoimmune conditions
* Type 1
** Associated with high IgG4 levels and obstructive jaundice in older men
** Often seen as part of an IgG4-related disease syndrome
*** Sclerosing cholangitis
*** Retroperitoneal fibrosis
*** Sclerosing sialadenitis
* Type 2
** Pancreas-specific disease - often presents with acute pancreatitis
** Often have normal IgG4
** Requires tissue sampling, as no biomarker
** 'idiopathic duct-centric pancreatitis'
** Often seen with IBD
* Diagnosis
** Histology in the setting of supportive serologic studies
** EUS and MRCP if suspected (also need to exclude pancreatic cancer)
* Treatment
** Glucocorticoid - typically dramatic response - if no response you need to suspect cancer

[[Category:Pancreas]]
[[Category:Intern education]]