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Large bowel obstruction

From Surgopaedia

Mechanical bowel obstruction distal to the ileocaecal valve.

Epidemiology

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  • Comprises 24% of admissions for mechanical bowel obstruction.
  • Surgery required in 70% of cases

Aetiology:

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Dynamic (mechanical)

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    • Luminal
      • CRC (50% of LBO)
        • Most commonly descending colon or rectosigmoid
      • Faecal impaction
      • Foreign body
      • Bezoar
    • Mural
      • Diverticular stricture
        • Often seen in Hinchey II disease, with an intramural or extramural abscess compressing bowel
        • If partial obstruction - generally resolves with conservative management
        • If complete - may need stenting/resection
      • Intussusception
        • In adults, almost always associated with a pathologic lead point
        • 46% malignant in colon
      • IBD stricture
        • More likely to be Crohn's (transmural)
      • Ischaemic/radiotherapy-induced strictures
        • Fibrosis
        • Radiation Therapy Oncology Group grading for radiation-induced bowel damage
      • Infection
        • Lymphogranuloma venereum
        • TB
        • Schistosomiasis
      • Hirschsprung disease
    • Extraluminal
      • Extraluminal obstruction - esp. ovarian cancer
      • Sigmoid Volvulus
        • See separate topic
      • Caecal volvulus
        • See separate topic
      • Hernia
      • Abdominal abscess
      • Retroperitoneal fibrosis
      • Adhesions (rare)

Adynamic (functional - pseudo-obstruction) - Ogilvie Syndrome

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    • See separate topic 'Pseudo-obstruction
    • Toxic megacolon
    • Paralytic ileus

Pathophysiology

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  • Distension of the colon occurs as a result of gas and stool that gather proximal to the obstruction
  • Pressure within the bowel wall can rise above the capillary pressure, diminishing adequate oxygenation, leading to ischaemic necrosis and perforation
  • Necrosis and perforation usually occurs in the caecum due to Laplace's law (largest diameter - will distend more under lower pressures and hence develop more wall stress)
  • Venous ischaemia can also develop due to mesenteric compression in strangulated hernias and volvulus

Presentation:

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  • Increased peristalsis and low-grade colicky pain
    • Late obstruction may have decreased bowel sounds
  • Acute obstructions can be dramatic rapid-onset pain, distension and tenderness
  • Chronic progressive obstructions may describe more of increasing constipation, pencil-thin stools, and intermittent pain
  • Functional obstructions usually have distension, vague abdominal pain, and weak or absent bowel sounds
  • Ask about weight loss, bleeding, bowel habits, night sweats. Check for hernias and incisions. DRE.
  • Classically, a mechanical obstruction will give a collapsed rectum, while a pseudo-obstruction will give a capacious rectum on DRE. Also need to exclude a synchronous rectal cancer.

Imaging

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  • Plain film - 'bent inner sign' pointing to RUQ (sigmoid volvulus) and coffee bean sign pointing to LUQ (caecal volvulus)
  • CT with IV contrast. According to Schein, no need for rectal or oral contrast
    • Contrast enema can be useful to evaluate distal causes of LBO (note use water soluble contrast, not barium, so it can't be absorbed into peritoneum if there is a perf)
  • Check for closed-loop obstructions
    • Competent ICV
    • Hernia
    • Volvulus

Management - tailored to aetiology and patient factors

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Medical management

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    • Fluid resus/electrolytes
    • Consider IDC
    • NGT for most patients
    • Stoma marking

Indications for immediate surgery

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    • Signs of perforation
    • Ischaemia, including closed loop (pneumatosis coli)
    • Peritonitis
    • Impending caecal perforation (diameter >10cm)
    • Tachycardia, hypotension, lactic acidosis

If no immediate indication for surgery - management by aetiology, the next day, once resuscitation has occurred.

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    • Luminal
      • CRC
        • See separate topic
        • Proximal to, and including, the splenic flexure - right hemicolectomy
        • Sigmoid/left colon - stenting as a bridge to surgery, or upfront surgery
        • Low and mid rectum - diversion to allow for neoadjuvant CRT
      • Faecal impaction
        • Stool softeners, manual disimpaction
      • Foreign body
        • Remove endoscopically
      • Bezoar
        • Remove endoscopically
    • Mural
      • Diverticular stricture
        • See separate topic
      • Intussusception
        • Surgery
      • IBD stricture
        • See separate topic - steroids
      • Ischaemic/radiotherapy-induced strictures
        • Low-residue diet, antibiotics, endoscopic therapy such as argon beam coagulation for colonic telangiectasias, balloon dilatation for strictures
        • May require intervention, most often for stricture
      • Infection
        • Lymphogranuloma venereum
        • TB
        • Schistosomiasis
      • Hirschsprung disease
    • Extraluminal
      • Extraluminal obstruction - esp. ovarian cancer
        • Treat the mass
        • Consider stent
      • Sigmoid Volvulus
        • See separate topic
      • Caecal volvulus
        • See separate topic
      • Hernia
        • Usually requires surgery
      • Abdominal abscess
        • Drain abscess
      • Retroperitoneal fibrosis
      • Adhesions (rare)

Choice of operation

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  • Right-sided obstructing lesion - right hemicolectomy
    • If perforation or peritonitis, ischemia or necrosis, poor nutrition, sepsis, immunosuppression or poor overall health, should have end ileostomy (70% of these will never get reconnected)
    • Self-expanding metal stent is also an option as a bridge to hemicolectomy
  • Left-sided obstructing lesions are a bit more diverse in options/less clear-cut
    • Hartmann's
    • Subtotal colectomy (if significant proximal colon dilatation or ischaemia)
    • Proximal diversion
    • Loop colostomy

Operation

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  • If the large bowel is severely distended and impeding view, decompress it with a 14G needle on a syringe with the plunger removed, and attach to suction. Put that needle through the tenia, ideally at a spot where you will make a hole anyway for the anastomosis. If that fails due to fecal build-up, put a Poole sucker through the hole.
  • If in doubt, do an oncologic resection
  • If there is a large fixed mass in the pelvis, don't try too hard to resect it
  • Consider on-table colonic lavage if doing an anastomosis, however UTD says not necessary
    • Divide distally and place the open distal end in a clean dish
    • Pass a 16Fr Foley through the base of appendix, run 4-6L of warm saline through until it comes out clear, then close the appendicectomy

Stenting

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  • Indications
    • Poor candidates for surgery
    • Locally advanced/metastatic disease (neoadjuvant CTX)
  • Technically possible in 90% of patients
  • Complications
    • Migration
    • Regrowth and re-obstruction
    • Perforation
  • Often used as a bridge to surgery
  • Surgery is still preferred if there's no need to optimise oncologic outcomes