Large bowel obstruction
Appearance
Mechanical bowel obstruction distal to the ileocaecal valve.
Epidemiology
[edit | edit source]- Comprises 24% of admissions for mechanical bowel obstruction.
- Surgery required in 70% of cases
Aetiology:
[edit | edit source]Dynamic (mechanical)
[edit | edit source]- Luminal
- CRC (50% of LBO)
- Most commonly descending colon or rectosigmoid
- Faecal impaction
- Foreign body
- Bezoar
- CRC (50% of LBO)
- Mural
- Diverticular stricture
- Often seen in Hinchey II disease, with an intramural or extramural abscess compressing bowel
- If partial obstruction - generally resolves with conservative management
- If complete - may need stenting/resection
- Intussusception
- In adults, almost always associated with a pathologic lead point
- 46% malignant in colon
- IBD stricture
- More likely to be Crohn's (transmural)
- Ischaemic/radiotherapy-induced strictures
- Fibrosis
- Radiation Therapy Oncology Group grading for radiation-induced bowel damage
- Infection
- Lymphogranuloma venereum
- TB
- Schistosomiasis
- Hirschsprung disease
- Diverticular stricture
- Extraluminal
- Extraluminal obstruction - esp. ovarian cancer
- Sigmoid Volvulus
- See separate topic
- Caecal volvulus
- See separate topic
- Hernia
- Abdominal abscess
- Retroperitoneal fibrosis
- Adhesions (rare)
- Luminal
Adynamic (functional - pseudo-obstruction) - Ogilvie Syndrome
[edit | edit source]- See separate topic 'Pseudo-obstruction
- Toxic megacolon
- Paralytic ileus
Pathophysiology
[edit | edit source]- Distension of the colon occurs as a result of gas and stool that gather proximal to the obstruction
- Pressure within the bowel wall can rise above the capillary pressure, diminishing adequate oxygenation, leading to ischaemic necrosis and perforation
- Necrosis and perforation usually occurs in the caecum due to Laplace's law (largest diameter - will distend more under lower pressures and hence develop more wall stress)
- Venous ischaemia can also develop due to mesenteric compression in strangulated hernias and volvulus
Presentation:
[edit | edit source]- Increased peristalsis and low-grade colicky pain
- Late obstruction may have decreased bowel sounds
- Acute obstructions can be dramatic rapid-onset pain, distension and tenderness
- Chronic progressive obstructions may describe more of increasing constipation, pencil-thin stools, and intermittent pain
- Functional obstructions usually have distension, vague abdominal pain, and weak or absent bowel sounds
- Ask about weight loss, bleeding, bowel habits, night sweats. Check for hernias and incisions. DRE.
- Classically, a mechanical obstruction will give a collapsed rectum, while a pseudo-obstruction will give a capacious rectum on DRE. Also need to exclude a synchronous rectal cancer.
Imaging
[edit | edit source]- Plain film - 'bent inner sign' pointing to RUQ (sigmoid volvulus) and coffee bean sign pointing to LUQ (caecal volvulus)
- CT with IV contrast. According to Schein, no need for rectal or oral contrast
- Contrast enema can be useful to evaluate distal causes of LBO (note use water soluble contrast, not barium, so it can't be absorbed into peritoneum if there is a perf)
- Check for closed-loop obstructions
- Competent ICV
- Hernia
- Volvulus
Management - tailored to aetiology and patient factors
[edit | edit source]Medical management
[edit | edit source]- Fluid resus/electrolytes
- Consider IDC
- NGT for most patients
- Stoma marking
Indications for immediate surgery
[edit | edit source]- Signs of perforation
- Ischaemia, including closed loop (pneumatosis coli)
- Peritonitis
- Impending caecal perforation (diameter >10cm)
- Tachycardia, hypotension, lactic acidosis
If no immediate indication for surgery - management by aetiology, the next day, once resuscitation has occurred.
[edit | edit source]- Luminal
- CRC
- See separate topic
- Proximal to, and including, the splenic flexure - right hemicolectomy
- Sigmoid/left colon - stenting as a bridge to surgery, or upfront surgery
- Low and mid rectum - diversion to allow for neoadjuvant CRT
- Faecal impaction
- Stool softeners, manual disimpaction
- Foreign body
- Remove endoscopically
- Bezoar
- Remove endoscopically
- CRC
- Mural
- Diverticular stricture
- See separate topic
- Intussusception
- Surgery
- IBD stricture
- See separate topic - steroids
- Ischaemic/radiotherapy-induced strictures
- Low-residue diet, antibiotics, endoscopic therapy such as argon beam coagulation for colonic telangiectasias, balloon dilatation for strictures
- May require intervention, most often for stricture
- Infection
- Lymphogranuloma venereum
- TB
- Schistosomiasis
- Hirschsprung disease
- Diverticular stricture
- Extraluminal
- Extraluminal obstruction - esp. ovarian cancer
- Treat the mass
- Consider stent
- Sigmoid Volvulus
- See separate topic
- Caecal volvulus
- See separate topic
- Hernia
- Usually requires surgery
- Abdominal abscess
- Drain abscess
- Retroperitoneal fibrosis
- Adhesions (rare)
- Extraluminal obstruction - esp. ovarian cancer
- Luminal
Choice of operation
[edit | edit source]- Right-sided obstructing lesion - right hemicolectomy
- If perforation or peritonitis, ischemia or necrosis, poor nutrition, sepsis, immunosuppression or poor overall health, should have end ileostomy (70% of these will never get reconnected)
- Self-expanding metal stent is also an option as a bridge to hemicolectomy
- Left-sided obstructing lesions are a bit more diverse in options/less clear-cut
- Hartmann's
- Subtotal colectomy (if significant proximal colon dilatation or ischaemia)
- Proximal diversion
- Loop colostomy
Operation
[edit | edit source]- If the large bowel is severely distended and impeding view, decompress it with a 14G needle on a syringe with the plunger removed, and attach to suction. Put that needle through the tenia, ideally at a spot where you will make a hole anyway for the anastomosis. If that fails due to fecal build-up, put a Poole sucker through the hole.
- If in doubt, do an oncologic resection
- If there is a large fixed mass in the pelvis, don't try too hard to resect it
- Consider on-table colonic lavage if doing an anastomosis, however UTD says not necessary
- Divide distally and place the open distal end in a clean dish
- Pass a 16Fr Foley through the base of appendix, run 4-6L of warm saline through until it comes out clear, then close the appendicectomy
Stenting
[edit | edit source]- Indications
- Poor candidates for surgery
- Locally advanced/metastatic disease (neoadjuvant CTX)
- Technically possible in 90% of patients
- Complications
- Migration
- Regrowth and re-obstruction
- Perforation
- Often used as a bridge to surgery
- Surgery is still preferred if there's no need to optimise oncologic outcomes