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Retroperitoneal abscess
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Primary - haematogenous or lymphatic seeding from a distant site Secondary - direct spread == Risk factors == * Primary ** Diabetes ** IVDU ** HIV ** Immunosuppression ** Focal trauma and haematoma formation * Secondary ** Infection in adjacent space ** Trauma and instrumentation == Aetiology (mostly attributable to local renal/GIT disease) == * Primary (haematogenous spread) * Secondary (infection in an adjacent organ) ** Renal disease *** Pyelonephritis *** Operations ** GIT disease *** Appendicitis *** Diverticulitis *** Crohn disease *** Pancreatitis ** Operative procedures *** Epidural ** Bone infections of spine *** TB == Pathophysiology == * Causative organism depends on organ of origin ** Kidney - GNB ** GIT - polymicrobial ** Haematogenous - staph ** Spine - E coli or TB == Presentation == * Classical triad - fever, back pain, and limp * Abdominal/flank pain (60-75%) * Fever and chills (30-90%) * Malaise (10-20%) * Weight loss (12%) * Frequently present 1-2 weeks after start of symptoms == Imaging == * Hypodense retroperitoneal mass * Contains gas in 30% == Natural history == * Stage 1 - insidious onset pain * Stage 2 - pain develops and localises, systemic features develop * Stage 3 - toxic sepsis == Management == * Antibiotics - long course, 2-3 weeks on UTD * CT-guided drainage (UTD says for all abscesses, successful 90%) * OT for those that fail IR or are not amenable, due to multiloculated abscess, necrosis or something else requiring intervention * Treat underlying cause [[Category:Abdo wall and retroperitoneum]]
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