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Refeeding syndrome
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== Risk factors == * BMI <16 * Significant weight loss in past 3-6 months * Sarcopaenia * No nutritional intake for past seven days * Pre-existing electrolyte derangements == Pathophysiology == * Rapid introduction of calories in a patient with malnutrition (pre-existing catabolic state) * Sudden influx of excess carbohydrates, results in higher insulin, and increases movement of phosphate and potassium intra-cellularly (also increased thiamine utilisation) * Leads to low potassium, magnesium, phosphate and a thiamine deficiency (phosphate is the first to drop) * Usually occurs within the first 72 hours of refeeding * Hypophosphataemia is the hallmark of refeeding syndrome, and generally manifests during the first week of re-feeding == Management == * Needs higher doses of electrolytes than would normally be given [[Category:Nutrition]] [[Category:Intern education]]
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