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Miscarriage
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Defined as the loss of an intra-uterine pregnancy at less than 24 weeks' gestation * Early miscarriage <12 weeks * Late miscarriage 12-24 weeks == Incidence == * About 20% of all pregnancies * Highly influenced by maternal age, reaching about 50% in a 45 year old woman == Presentation == * Threatened miscarriage: vaginal bleeding with closed os * Inevitable miscarriage: bleeding, cramps, open os * Complete miscarriage: empty uterus * Incomplete miscarriage: retained products of conception * Missed miscarriage: no fetal heart beat, but no clinical signs of miscarriage == Differential diagnosis of vaginal bleeding in pregnancy: == * Cervical lesion * Trauma == Imaging == * Diagnosed based on transvaginal scan with absent fetal heart beat and a crown-rump length of 7mm or more; or, in the absence of a fetal pole in the presence of a mean gestational sac diameter of 25mm or more == Management == * Expectant * Medical ** Prostaglandins (supports uterine contractions and cervical softening) * Surgical ** Indications: *** Persistent excessive bleeding *** Haemodynamic instability *** Evidence of retained tissue *** Suspected gestational trophoblastic disease ** Vacuum pump aspiration ** Suction curette (GA) ** Consider rhesus status [[Category:O+G]]
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