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Mallory-Weiss tear
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Linear mucosal or submucosal lacerations at or near GOJ resulting from forceful retching/vomiting that may lead to UGIB. * Initially described by Kenneth Mallory and Soma Weiss in 1929 == Pathophysiology == * Results from large gradient in pressure between stomach and thorax, which occurs at GOJ * Can result from 'any action which results in an abrupt increase in intra-abdominal pressure and gastric herniation' ** Vomiting ** Coughing ** Straining * Most tears occur below GOJ (within 2cm), and along lesser curve == Risk factors == * Hiatus hernia (found in 50% of cases) * 40-60 year old patients * Aspirin/alcohol can make bleeding worse == Risks for worse outcomes == * Older * Anaemia * Shock at presentation * Active bleeding on endoscopy * Alcoholic patients with portal hypertension == Presentation == * Non-bloody vomiting followed by haematemesis is classic * Seen in 5-15% of patients with UGIB (behind only PUD in non-variceal UGIB) * MOSTLY self-limiting == Treatment approach == * Generally identified during initial endoscopy for UGIB - treat with adrenaline and gold probe, or haemoclip if gold probe is unavailable * If patient becomes unstable again, or there is large bleeding and you are unable to get control endoscopically, consider transarterial embolisation if available * If all else fails, operate == Management options == * Medical ** PPI (raises gastric pH to improve coagulation) ** Anti-emetic * Endoscopic intervention if active bleeding ** 90-100% success rate ** Injection therapy *** Adrenaline 1-3mL of 1:10,000 **** Mix 1mL of 1:1000 adrenaline with 9mL saline **** Great outcomes but combine with second therapy *** Sclerosing agents ** Multipolar electrocoagulation ** Band ligation ** Haemoclipping * Interventional embolotherapy * Surgery ** Very rarely indicated ** High anterior longitudinal gastrotomy to visualise GOJ mucosa ** Oversew with 2/0 Vicryl to reappose mucosa [[Category:UGIS]]
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