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Intramural endoscopic surgery
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AKA 'third-space endoscopy' == Procedures == # POEM # Peroral pyloromyotomy for gastroparesis (gastric-POEM) # Submucosal tunnelling endoscopic resection of subepithelial tumours (STER) # Flexible endoscopic diverticulotomy for Zenker (FED) # Peroral endoscopic tunneling for restoration of the oesophagus (POETRE) == Basic principles == * Use of the submucosal plane, which is the plane between mucosa and muscularis propria, comprised of loose areolar tissue * GA is highly preferable * Abx should include antifungals * Diagnostic endoscopy is performed == Procedure == * Initial submucosal bleb injection with mucosal flap incision - make sure it's of appropriate distance from the planned myotomy site - you want a bit of distance to allow this submucosal tunnel to act as a flap/valve if you perforate distally at the myotomy site ** Can use a mixture incorporating methylene blue, adrenaline and saline to raise the bled (the dye helps to identify the submucosa) ** If you don't see a weal developing, you're probably too deep, and need to draw back * Creation of submucosal tunnel - use short bursts of electrocautery - may need repeated injections of submucosal fluid * Myotomy/lesion excision * Mucosal flap closure - easiest with haemostatic clips == Post-procedure == * Baseline erect CXR * Get another CXR if patient deteriorates clinically * Upper GI contrast study on day 1 - looking for leak or obstruction ** If no major issues, start on liquid diet * Most patients stay 24 hours or so * Liquid diet 1-2 weeks * PPI +/- sucralfate to prevent ulceration at myotomy [[Category:Endoscopy]]
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