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Pancreatic lesions
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== '''Acinar cell carcinoma''' == * Rare, with unique features * Arise from acinar cells - site of synthesis of exocrine enzymes * Risk factors ** Mid-50s ** Males * Presentation ** Non--specific symptoms ** Often >5cm at diagnosis ** Sometimes generate lipase - can cause paraneoplastic syndromes in some patients *** Polyarthralgia *** Eosinophilia *** Subcutaneous fat necrosis and rashes ('pancreatic panniculitis') ** Mostly malignant - should be resected ** Better prognosis than PDAC
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