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== Head and neck == * Pharyngeal (previously called branchial) arches consist of bars of mesenchymal tissue separated by pharyngeal clefts ** Form in about the fourth week ** A core of mesenchymal tissue covered on the outside by surface ectoderm and on the inside by endodermal epithelium ** Each arch contains its own artery (aortic arch), cranial nerve, muscle element, and cartilage bar or skeletal element ** These arches play important roles in facial development ** The fifth arch disappears during development and does not lead to any structures *[[File:Table - derivatives of arches.png|frameless|663x663px]] * [[File:Derivatives of pouches.png|right|frameless]]Endodermal pharyngeal pouches form simultaneously along the lateral walls of the pharynx ** Embryo has four pairs of pouches - the fifth is rudimentary ** These pouches penetrate the surrounding mesenchyme but do not establish an open communication with the external clefts; so the whole structure is not really analogous to gills ** Endoderm of the pharyngeal pouches gives rise to a number of endocrine glands and parts of the middle ear * Pharyngeal clefts are transient structures that all disappear, but in some cases can persist as cervical cysts/fistulas
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