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== '''Tumour markers''' == * AFP can be elevated, but overall sensitivity and specificity are low ** False positives with inflammatory disorders of the liver, intra-hepatic cholangiocarcinoma, colorectal mets, germ cell tumours elsewhere e.g. testes ** Better for surveillance than diagnosis ** AFP > 400 is associated with an 'almost definite' diagnosis of HCC, once differentials are excluded, according to Eunice
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