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== '''Lymphatic drainage:''' == * Abundant lymphatics in the breast parenchyma and dermis * 'Sappey plexus' located under the NAC. Lymph flows from skin to subareolare Sappey plexus, then into the interlobular lymphatics of breast parenchyma * Sentinel node location: ** 75% of breast lymph passes to axillary lymph nodes, mainly to anterior nodes, some to posterior nodes; direct drainage to central or apical nodes is possible. ** 25% to parasternal nodes along the internal thoracic artery (5% sole pathway, 20% shared with axilla) * Can drain to posterior intercostal nodes. * Occasionally, can drain to infraclavicular nodes in the deltopectoral groove * Direct drainage from breast to supraclavicular nodes is possible * These minor pathways tend to only convey lymph from breast when the major channels are obstructed by malignant disease.
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