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Vasculitis
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== '''Medium-vessel vasculitis''' == * Polyarteritis nodosa ** Pathophysiology *** Necrotising vasculitis or small and medium arteries *** Characterised by the absence of glomerulonephritis and absence of ANCA antibodies *** Can be idiopathic or secondary to HBV infection or other viral infections *** Also seen as a paraneoplastic manifestation of haematology malignancy ** Diagnosis *** ** Presentation *** Constitutional symptoms and organ dysfunction - see above * '''Thromboangitis obliterans (Buerger disease)''' ** See separate topic) * '''Kawasaki disease''' ** Acute vasculitis ** Typically seen in children ** Involvement of small/medium arteries, especially coronary arteries ** Main cause of death is MI ** Treat with high-dose aspirin and IVIg
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