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Pleural effusions
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=== '''Causes of exudative pleural effusions''' === {| class="wikitable" | {| class="wikitable" |'''Infectious''' |- |Bacterial pneumonia |- |Tuberculous pleurisy |- |Parasites |- |Fungal disease |- |Viral pneumonias (eg, influenza, coronavirus disease 2019 [COVID-19]) |- |Nocardia, Actinomyces |- |Subphrenic abscess |- |Hepatic abscess |- |Splenic abscess |- |Hepatitis |- |Spontaneous esophageal rupture |- |Cholecystitis |- |'''Iatrogenic or trauma''' |- |Central venous catheter misplacement/migration |- |Drug-induced (eg, nitrofurantoin, dantrolene, methysergide, dasatinib, amiodarone, interleukin-2, procarbazine, methotrexate, clozapine, phenytoin, beta blocker, ergot drugs) |- |Esophageal perforation |- |Esophageal sclerotherapy |- |Enteral feeding tube in pleural space |- |Radiofrequency ablation of pulmonary neoplasms |- |Hemothorax |- |Chylothorax |- |'''Malignancy-related''' |- |Carcinoma |- |Lymphoma |- |Mesothelioma |- |Leukemia |- |Chylothorax |- |Paraproteinemia (multiple myeloma, Waldenstrom's macroglobulinemia) |- |Paramalignant effusions |- |'''Other inflammatory disorders''' |- |Pancreatitis (acute, chronic) |- |Benign asbestos pleural effusion |- |Pulmonary embolism |- |Radiation therapy |- |Uremic pleurisy |- |Sarcoidosis |- |Postcardiac injury syndrome |- |Acute respiratory distress syndrome (ARDS) |- |Immunoglobulin G4-related disease (fibroinflammatory) |} | {| class="wikitable" |'''Increased negative intrapleural pressure with accompanying pleural malignancy or inflammation''' |- |Lung entrapment |- |Cholesterol effusion (eg, due to tuberculosis, rheumatoid arthritis) |- |'''Connective tissue disease''' |- |Lupus pleuritis |- |Rheumatoid pleurisy |- |Mixed connective tissue disease |- |Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) |- |Granulomatosis with polyangiitis (Wegener's) |- |Familial Mediterranean fever |- |'''Endocrine dysfunction''' |- |Hypothyroidism |- |Ovarian hyperstimulation syndrome |- |'''Lymphatic abnormalities''' |- |Malignancy |- |Chylothorax (eg, yellow nail syndrome, lymphangioleiomyomatosis, lymphangiectasia) |- |'''Movement of liquid from abdomen to pleural space''' |- |Pancreatitis |- |Pancreatic pseudocyst |- |Meigs' syndrome |- |Chylous ascites |- |Malignant ascites |- |Subphrenic abscess |- |Hepatic abscess (bacterial, amebic) |- |Splenic abscess, infarction |- |'''Miscellaneous''' |- |Endometriosis |- |Drowning |- |Electrical burns |- |Capillary leak syndromes |- |Extramedullary hematopoiesis |} |}
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