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Barrett's oesophagus
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== '''Evaluation:''' == * Careful endoscopy - white light and NBI are both useful ** Suspect when GOJ (proximal extent of rugae) is >=1cm distal to the z-line ** Barrett's has a characteristic salmon pink colour and velvety texture ** Firstly identify the segment of columnar epithelium, and also look for areas of irregularity within it ** Use Prague classification system (see 'endoscopy' topic) ** Note hiatal hernias ** Seattle protocol for biopsies * Oesophagitis + Barrett's ** If LA C or D oesophagitis is found, the pathologist will have trouble identifying dysplasia and a diagnosis of 'indeterminate' is likely ** If no concerns for cancer, put them on high-dose PPI and re-scope in 6-8 weeks * Irregular z-line: ** Found in 10-15% of patients ** When the SCJ lies above the GOJ, but without any confluence, forming tongues shorter than 1cm, and thus does not fulfil criteria for BO ** It can harbour histological intestinal metaplasia, but the progression rate to BO is low, let alone to malignancy, so no further evaluation or screening is recommended
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