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== '''Aetiology''' == * Obstruction can be caused by: ** Mechanical obstruction with faecalith/appendicolith due to stasis ** Lymphoid hyperplasia ** Parasitic infection (ascaris or pinworm) *** Pinworms (Enterobius vermicularis) are the small white wriggling ones - treat with mebendazole one tablet stat and then repeat dose in two weeks, and also need to treat any household contacts ** Neoplasm (1% of acute appendicitis) ** Fruit and vegetable material ** Ingested barium * However these are not always present. Genetic factors, environmental influences, and infections may play a role. ** Twin studies suggest about 30% of variation in risk for appendicitis is from genes ** Seems to occur more often in summer ** Clusters of presentation occur, suggesting maybe infection. ** Certain bacteria, especially Fusobacterium, seem to increase the risk of perforation when present
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