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Pleural effusions
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=== '''Causes of transudative pleural effusions''' === {| class="wikitable" |'''Causes of transudative effusions''' |'''Comment''' |- |'''Processes that ''always'' cause a transudative effusion''' | |- |Atelectasis |Caused by increased intrapleural negative pressure |- |Cerebrospinal fluid leak into pleural space |Thoracic spinal surgery or trauma and ventriculopleural shunts |- |Heart failure |Acute diuresis can result in borderline exudative features |- |Hepatic hydrothorax |Rare without clinical ascites |- |Hypoalbuminemia |Edema liquid rarely isolated to pleural space |- |Iatrogenic |Misplaced intravenous catheter into the pleural space; post Fontan procedure |- |Nephrotic syndrome |Usually subpulmonic and bilateral |- |Peritoneal dialysis |Acute massive effusion develops within 48 hours of initiating dialysis |- |Urinothorax |Caused by ipsilateral obstructive uropathy or by iatrogenic or traumatic GU injury |- |'''Processes that ''may'' cause a transudative effusion, but ''usually'' cause an exudative effusion''' | |- |Amyloidosis |Often exudative due to disruption of pleural surfaces |- |Chylothorax |Most are exudative effusions |- |Constrictive pericarditis |Bilateral effusions |- |Hypothyroid pleural effusion |From hypothyroid heart disease or hypothyroidism per se |- |Malignancy |Usually exudative, but 3 to 10 percent transudative possibly due to early lymphatic obstruction, obstructive atelectasis, or concomitant disease (eg, heart failure) |- |Pulmonary embolism |Most are exudative effusions |- |Sarcoidosis |Stage II and III disease |- |Superior vena caval obstruction |May be due to acute systemic venous hypertension or acute blockage of thoracic lymph flow |- |Coronavirus disease 2019 (COVID-19) |Limited data profile the nature of pleural fluid in COVID-19-related pleural effusions, although transudative effusions have been reported |- |Nonexpandable lung* |A result of remote or chronic inflammation |}
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