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Crohn's disease
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=== Obstruction === * Much more common in CD than UC - intermittently - can be inflammatory/fibrotic stricture, but can also be adhesive due to previous surgery * Aetiology ** Secondary to an acute exacerbation of active disease *** Typically improve with medical management (IV corticosteroids) ** Secondary to chronic fibrosing lesions (most patients with complete SBO fall into this group) *** Most commonly TI *** Trial non-op - often partial obstruction **** No benefit to steroids - often require surgery - complete obstruction often requires resection **** If doubt over presence of acute inflammation, can do faecal calprotectin *** Look to intervene if no improvement in 48 hours, according to Schein **** Operation of choice is segmental resection and primary anastomosis **** Consider stricturoplasty - when bowel resection is inappropriate due to risk of short bowel syndrome in patients with extensive fibro-stenotic disease, or in patients with multiple short-segment strictures over a longer area of bowel, several previous bowel resections, and in those with chronic fibrous obstruction. Complication and recurrence rates are comparable to resection with anastomosis in this setting. **** **** Endoscopic dilation - initial success rate 90% for fibrotic strictures however 75% of patients require further dilation **** Needle-knife stricturotomy can also be used - not widely-accepted yet **** Large bowel strictures, particularly UC, raise concern for malignancy. Do a full oncologic resection if operating in this setting. Stricturoplasties are not recommended in colon.
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