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Meckel's diverticula
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== Pathophysiology == * Remnant of proximal vitelline (omphalomesenteric) duct (connects embryonic midgut to the yolk sac). Results from incomplete closure. * Lined by pluripotent cells - therefore, can find heterotopic tissue inside ** Usually normal ileal mucosa ** Gastric mucosa in 50% ** Pancreatic mucosa in 5% ** Colonic mucosa rarely * Projects from antimesenteric border 45-60cm from ICV. * Ranges from a small bump to a long projection communicating with the umbilicus * Typically about 5cm long and 2cm wide * Rule of twos: ** 2 feet from ICV ** 2% of population ** Symptomatic in 2% of cases (usually within first 2 years of life) ** Usually less than two inches/5cm in length
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