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Lymphoedema
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== Aetiology == * Primary ** Much more common in females ** Often unilateral ** See below for age-related classification ** Congenital <1yo - Milroy's disease *** Congenital absence, defective function or obstruction of lymphatics *** One or both lower limbs ** Lymphoedema praecox <35yo *** The most common form of primary lymphoedema, usually involving only calf and foot, usually unilateral, and typically beginning at puberty ** Lymphoedema tarda >35yo * Secondary ** Surgery ** Cancer - related to treatment and following factors - most common in developed world *** Obesity *** Extent of surgery *** Delayed wound healing *** Post-op infection *** Haematoma/seroma ** Filariasis *** Infestation with parasites (Wucheria bancrofti, Brugia malayi, Brugia timori) *** Most common cause in developing countries *** Transmitted by mosquitos - adult worm lives in nodes and releases larvae at night - followed by fibrosis of nodes and elephantiasis *** Rapidly develops into elephantiasis - extremely difficult to treat ** Burns ** Large/circumferential extremity wounds ** Pregnancy ** Bacterial/fungal infections ** Infections after snake or insect bites ** Contact dermatitis ** Rheumatoid arthritis
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