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Hyperthyroidism
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== '''Aetiology''' (most commonly those in bold) == * '''Associated with normal or high RAI uptake''' (indicates de novo synthesis of hormone, so can be treated with a thionamide (i.e. carbimazole)) ** '''Graves disease''' ** '''TMNG''' ** '''Toxic adenoma''' ** Trophoblastic disease ** TSH-producing pituitary adenoma ** Thyroid hormone resistance * '''Associated with no or minimal RAI uptake''' (indicates either inflammation and destruction of thyroid tissue with release of pre-formed hormone into the circulation, or an extra-thyroidal source of thyroid hormone; so thionamides won't help in these disorders) ** Thyroiditis *** Painless thyroiditis (silent or lymphocytic) *** Amiodarone-induced thyroiditis *** Subacute granulomatous thyroiditis *** Acute thyroiditis *** Palpation thyroiditis ** Iatrogenic thyrotoxicosis - excessive, intentional replacement, or factitious ** Struma ovarii ** Follicular thyroid cancer metastases (ectopic)
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