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Upper GI bleed
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=== '''Third-line: surgery (needed in 5-10%)''' === ** Indications: *** Failed endoscopy x2 *** Haemodynamically unstable despite vigorous resus (>3 units) **** Previously, >= 6 units in index 24 hrs was indication for surgery *** Recurrent haemorrhage after haemostasis with endoscopy (reasonable to try twice with endoscopy) *** Ongoing transfusion requirement >3 units per day *** Unable to transfuse (rare blood type, refusal of transfusion) ** Technique *** Upper midline laparotomy (bleeding duodenal ulcers can technically be treated laparoscopically, but difficult) *** Examine for external signs of ulcer - will often be able to see serosal inflammatory changes at the site of a chronic ulcer *** If any doubt as to location, use intra-operative gastroscopy ** Duodenal ulcers: intervention will usually be to oversew or ligate bleeding vessel, which is the '''GDA''' at the base of a posterior ulcer *** May need a Kocher maneuvre to mobilise the duodenum and get manual control *** Longitudinal duodenotomy/pyloroduodenotomy from pylorus through to anterior wall of D1/D2 *** Remove blood, isolate bleeding *** Apply pressure and time for anaesthetics to catch up *** Underrun bleeding vessel with 3-point U-stitch technique of 2/0 Vicryl **** Careful of CBD - can insert a probe through the ampulla if necessary - although Mosche says he has never heard of it being sutured over **** Classically need to suture ligate GDA superiorly and inferiorly (12 and 6 o'clock), with another suture at 3 o'clock for transverse pancreatic branch *** Close the duodenotomy transversely (like a stricturoplasty) *** Consider vagotomy or other acid-reducing operation, but this is generally unnecessary nowadays ** Gastric ulcers *** Use the simplest possible operation that will stop the bleeding *** First gastrotomy and underrun the bleeding ulcer (30% rebleeding risk) *** Wedge resection may be a good option for greater curvature ulcers, but this gives a 10% rebleeding risk, so distal gastrectomy is favoured *** Bleeding proximal ulcers near GOJ are quite difficult to manage - proximal or near-total gastrectomy has very high mortality in setting of haemorrhage. Perhaps a distal gastrectomy with a tongue of proximal stomach, or a wedge resection/buttressed oversewing of the ulcer?
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