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Oesophagus
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== '''Tissue architecture''' == * Two main layers (no serosa, unlike the rest of the alimentary tract) ** '''Mucosa''' - mostly stratified squamous non-keratinizing epithelium, up to the Z-line, where it transitions to cardiac mucosa/junctional columnar epithelium *** Four distinct layers within the mucosa: **** Epithelium **** Basement membrane **** Lamina propria **** Muscularis mucosae - longitudinal fibres ** '''Submucosa''' is found deep to muscularis mucosae - strongest layer for holding sutures *** Lymphatic and vascular networks *** Mucous glands *** Meissner neural plexus *** Fibrous tissue ** '''Muscularis propria''' *** Inner circular layer (continuation of cricopharyngeus) **** Transitions from the circular muscles of the oesophagus to the oblique muscles of the stomach at the incisura, known as the collar of Helvetius *** Thin septum of connective tissue, which also contains the Auerbach plexus (interconnected ganglia) *** Outer longitudinal muscle layer **** Begins at back of cricoid cartilage by a tendon which gives rise to two fasciculi which spread out to constitute the longitudinal muscle **** Extends into abdomen, becoming the longitudinal muscle of the cardia of the stomach *** Proximal third predominantly striated muscle; distal third entirely smooth muscle; middle third a mixture * Final outside layer of '''fibroalveolar adventitia''' *
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