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Pleural effusions
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== '''Management of malignant and paramalignant pleural effusions''' == {| class="wikitable" |'''Option''' |'''Comment''' |- |Observation |For asymptomatic effusions; most will progress and require therapy |- |Therapeutic thoracentesis |Prompt relief of dyspnea; most effusions recur unless underlying tumor responds to chemo- or radiotherapy |- |Chest catheter drainage only |Most effusions will recur after catheter removal |- |Chest catheter drainage with chemical pleurodesis (eg, talc slurry) |Variable response rate with 60 to 90 percent of patients responding to talc pleurodesis |- |Thoracoscopy with talc insufflation |Control of effusion with similar frequency as chest catheter drainage with talc pleurodesis |- |Long-term indwelling pleural catheter |Control of effusion and improved symptoms in most patients. Some patients may experience pleurodesis after two weeks (median 11 weeks) of catheter drainage, which allows catheter removal. |- |Long-term indwelling pleural catheter with talc instillation |Control of effusion and symptoms with successful pleurodesis in 43 percent of patients without hospitalization |- |Pleural abrasion or pleurectomy |Requires thoracoscopy or thoracotomy. Effectively controls effusions in nearly all patients. |- |Pleuroperitoneal shunt |When other options have failed or are not indicated; may be useful for chylothorax |- |Chemotherapy |May be effective in some tumor types, such as breast cancer, lymphoma, and small cell lung cancer |- |Radiotherapy |Mediastinal radiation therapy may be effective in lymphoma and lymphomatous chylothorax |} Traditional criteria for indwelling pleural catheter removal - <50mL drainage for three consecutive days [[Category:Thoracics]] [[Category:Intern education]]
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