Editing Transplant immunology (section)

== Components to check ==

* Major Histocompatibility Complex (MHC) 
** Type I: all cells (HLA-A, B, C)
** Type II: antigen-presenting cells (HLA-DP, DQ, DR)
** The greater the degree of match, the better the outcome
** HLA-DR, HLA-B and HLA-A are the most important
* Direct cross-match
** Performed immediately before transplant
** Lysis of donor lymphocytes/complement suggests hyperacute rejection will occur
* Flow cytometry cross-match
** Binding of non-complement fixing Ab in recipient serum to donor lymphocytes indicates increased risk acute rejection
* Panel reactive Ab
** Can be tested for each potential recipient to generic Abx
** Patients previously sensitised will have higher levels, and will likely then have positive cross-match to more donors
* Mixed lymphocyte reaction
** Used for living donation