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Pericardial effusion/tamponade
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== Aetiology of '''effusion''': (virtually any disease that involves the pericardium can cause an effusion) == * Idiopathic ** Often seen as asymptomatic effusions in otherwise healthy people * Infectious ** Viral - echovirus, coxsackievirus, adenovirus, CMV, HBV, IMN, HIV/AIDS, SARS-CoV-2 ** Bacterial ** HIV-associated ** Fungal ** Protozoal * Inflammatory ** Autoimmune - SLE, RA, scleroderma, dermatomyositis, Sjogren syndrome, IBD ** Drug-induced autoimmune diseases - procainamide, hydralazine, isoniazid, cyclosporine ** Arteritis - polyarteritis nodosa, temporal arteritis ** Post-MI (Dressler syndrome) ** Miscellaneous - sarcoidosis, Erdheim-Chester disease, Churg-Strauss disease, IgG4 disease * Cancer (20%) ** Malignant involvement - either by direct invasion or lymphatic seeding, having first involved mediastinal nodes. Tumour must involve epicardium to cause an effusion. ** Primary - mesothelioma, fibrosarcoma, lipoma ** Secondary - breast and lung carcinoma, lymphomas, Kaposi sarcoma * Radiation-induced * Early post-cardiac surgery * Haemopericardium ** Trauma ** Post-MI free wall rupture ** Endomyocardial biopsy ** Dissecting aortic aneurysm ** Device and procedure-related ** Oral anticoagulants * Congenital * Miscellaneous ** Chronic renal failure ** Pulmonary HTN ** Hypothyroidism ** Protein malnutrition ** Cholesterol ** Amyloidosis ** Polycystic kidney disease
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