Editing Aortoiliac occlusive disease (section)

== Pathophysiology ==

* AIOD typically begins at aortic terminus and COA origins and slowly progresses proximally and distally
* Claudication symptoms can often be managed easily non-operatively for years due to good collaterals (lumbar and hypogastric arteries connecting to circumflex iliac, hypogastric, femoral, PFA recipients), and rarely leads to CLTI
* 40% have concomitant SFA disease and 35% have orifical PFA disease
* Generally doesn't progress proximally to level of visceral arteries
* 'Small aortic syndrome' or 'hypoplastic aortic syndrome' 
** Typically found in young women smoke
** Focal stenosis posteriorly at or proximal to the aortic bifurcation
** Durability of endovascular intervention or endarterectomy is often poor, especially if they keep smoking
* Leriche syndrome
** Impotence
** Claudication
** Lower extremity pallor and atrophy of leg muscles
** Absent femoral pulses
* Pelvic ischaemia
** Hip and buttock claudication, erectile discomfort, cauda equina syndrome